Annatto • Delta + Gamma
What aretocotrienols?
A small seed. A fascinating science.
Meet delta- and gamma-tocotrienol: two lesser-known members of the vitamin E family, found in annatto and explored in nutritional research.
botanical source
at the center of our formula
vitamin E family
The 30-second introduction
One family.
Two forms to know.
Tocotrienols are naturally occurring, fat-soluble compounds in the vitamin E family. Here, the focus is on delta and gamma from annatto—two distinct forms with their own molecular identities.12
A closer look
Small structure.
Big curiosity.
Delta and gamma share a tocotrienol signature: a chromanol ring joined to a side chain with three double bonds. This structure is part of what makes tocotrienols an interesting subject for research.3
The ring participates in antioxidant chemistry—reactions involving unstable molecules called free radicals.
Because tocotrienols are fat-soluble, researchers study their behavior in lipid-rich environments, including cell membranes.
Double bonds in the side chain.
A shared feature of delta and gamma.
The source matters
Why start
with annatto?
Annatto is the seed source behind the delta- and gamma-tocotrienols in our formula. Annatto-derived extracts let us focus on these two forms and make the botanical origin clear.
Explore the annatto differenceFollow the evidence
Read the science.
Know the context.
Interesting research starts with good questions. Understanding the type of study helps you see what its findings can—and cannot—tell you.
How do they behave?
Laboratory experiments explore antioxidant chemistry and cellular responses. A result in a test tube or cell culture does not establish a benefit in people.
What happens in a model?
Animal studies investigate absorption, tissue distribution and biological pathways. Findings help shape new questions, but do not directly predict human outcomes.
What do trials measure?
Human studies investigate particular formulations, amounts and outcomes. The participants, study length and exact ingredient all matter when interpreting results.
12 weeks.
Annatto tocotrienols in a human trial
A 2018 randomized trial studied an annatto extract containing delta and gamma in postmenopausal women with low bone mass. Researchers evaluated safety markers and other measures.
Liver and kidney markers showed no adverse changes during the study. Quality of life and body composition did not improve. These findings concern the studied extract and population, not proof of benefits from our finished product.
The study was funded by its ingredient supplier. One short-term trial does not establish long-term safety or effectiveness for everyone. Tocotrienol research is developing; supplements are not disease treatments.
Stay curious
A few things
worth asking.
Clear answers to the questions that come up when you look beyond the ingredient name.
Is “vitamin E” one single ingredient?
No. Vitamin E is a family of eight naturally occurring forms. This page focuses specifically on annatto-derived delta- and gamma-tocotrienol. The form matters when you read a label or a study.1
Why focus on delta and gamma?
These are the tocotrienol forms in our annatto-derived formula. A focused composition makes it easier to understand the botanical source and the ingredients you are choosing.
Check the product label for the amount per serving. A study using one extract or dose is not automatically evidence for every product with a similar ingredient name.
Do tocopherols stop tocotrienols from working?
That is too broad a conclusion. Some animal studies found that alpha-tocopherol affected the tissue accumulation of certain tocotrienols. Effects varied with the form and study conditions; this does not establish that every combination is ineffective in people.45
Our focus here is the identity and source of annatto-derived delta and gamma, rather than a blanket claim that other vitamin E forms cancel them out.
What does “antioxidant” actually mean?
An antioxidant can participate in reactions that limit oxidation involving free radicals. Free radicals arise during normal metabolism and from environmental exposures.
Reactive molecules also have normal roles in cell signaling. Antioxidant activity in a laboratory is not, by itself, proof that taking a supplement produces a particular health result.1
What should I look for on a product label?
Look for the named tocotrienol forms, the botanical source, the amount per serving and the other ingredients. If you are comparing a product with research, check whether the formulation and dose actually match.
Use the label directions and ask a qualified clinician about individual suitability, particularly if you take medication.
Get to know our formula
The source is annatto.The focus is clear.
Our DeltaPOWER™ formula features annatto-derived delta- and gamma-tocotrienols. Explore the product page for the ingredient list, serving information and directions.
Know the ingredients. Read the label. Choose thoughtfully.

