Discover the Power of Annatto…
What to know about the new Incredible Vitamin
Annatto is the only known Plant in the entire Plant Kingdom that produces this New form of Vitamin E (Tocotrienols) and is Void of the old Vitamin E (Tocopherols) that interfere with it.
Vitamin E:
Vitamin E is a family of eight different natural molecules.
Four (4) old “Tocopherols” and four (4) new “Tocotrienols”.
Each group has Alpha-, Beta-, Gamma- and Delta- forms.
All Vitamin E’s are tadpole shaped, with a head and a tail.
The only difference between the two groups is in the tail.
Tocotrienols have three unique double bonds in their tails.
Tocopherols (common) have no double bonds in their tails.
Tocotrienols:
The Tail of Tocotrienols provides its magical gifted benefits.
Tocotrienols are man’s “Bodyguards” protecting all of our cells.
Tocotrienols are powerful Antioxidants that protect us from the hordes of “Free Radicals” that attack our body every second.
Free Radicals are unstable, reactive molecules that damage DNA, proteins, and lipids (fats) in the body causing Oxidative Stress.
Oxidative Stress leads to aging (wrinkles, grey hair, loss of skin elasticity), cardiovascular disease (heart and blood vessels), most cancers, neurodegenerative diseases (Alzheimer’s, Parkinson’s, dementia), inflammatory diseases (arthritis, lupus, etc.)
Oxidative Stress (Free Radicals) are fought by “Antioxidants”.
Antioxidants are special molecules that can stop Free Radicals.
Tocotrienols are the ultimate fat-soluble Antioxidant in our body.
Delta- Tocotrienol is the smallest and fastest of all vitamin E forms.
Delta- & Gamma- Tocotrienols protect against lipid (fat) oxidation that degrades all fatty membranes making them rancid and dysfunctional.
Tocotrienols boost the Master antioxidant Glutathione in cells.
Delta- Tocotrienol can penetrate the Blood Brain Barrier (BBB) to target damaging Amyloid-beta and Tau tangles of Alzheimer;s disease and protect Dopamine-producing Neurons in Parkinson’s Disease.
Delta -Tocotrienols can increase the Antioxidant Enzymes such as Superoxide Dismutase (SOD), Catalase, Glutathione Peroxidase, etc.
Geranylgeraniol:
Geranylgeraniol (GG) is a natural occurring chemical compound found in all plants and animals and indispensable for all life on this planet.
In plants, GG is a vital precursor needed to make Chlorophyll, the green pigment required for photosynthesis or there could be No Life.
GG is the precursor to make Carotenoid pigments (beta-carotene, lycopene, lutein) - healthful nutrients in colordul fruits and vegetables.
GG is the precursor to plant sterols and allows only plants - not animals - to manufacture vitamins: B1 (thiamine), B2 (riboflavin), B3 (niacin), B6 (pyridoxine), vitamin A (retinol, retinoic acid), and vitamin E.
The Annatto plant uses Geranylgeraniol (GG) in its unique synthesis of Delta- Tocotrienols (90%) and Gamma- Tocotrienols (10%).
GG is a key intermediate precursor in the Mevalonate Pathway, which is crucial for Cholesterol Synthesis and the production of many other vital Biomolecules absolutely needed in all humans.
GG is needed to make Heme for Hemoglobin that carries oxygen to our cells and removes the waste by-product carbon dioxide.
GG is the vital building block to make CoQ10 for mitochondria to make the vital energy molecule ATP - Adenosine TriPhosphate.
GG is the vital building block in the synthesis of vitamin K2 (MK4) involved in the transport of calcium out of our blood vessels and soft tissues back into our bones and teeth.
GG is the vital precursor in the active synthesis of our skeletal muscle protein and preserves bone during our entire lifespan.
GG is a precursor to Squalene which is a precursor to Cholesterol and other Sterols, including our sex hormones.
GG influences Cell Signaling pathways, Mitochondrial function, and Apoptosis in all of our cells and tissues.
Geranylgeraniol (GG) is truly indispensable for human life itself.
For Maximum Benefits:
Tocotrienols & GG must be kept cool and be taken properly.
Tocotrienols & GG are sensitive to exposure to light, heat, air or oxidizing agents, metal ions, & extremes of pH (acid-base).
RDA (2000) for Vitamin E for the average adult is only 15 mg/day.
Totally insufficient for today’s active adult with 37+ trillion cells.
Vitamin E is low in foods, e.g. a whole avocado has only 4 mg!
Vitamin E needs to be supplemented for man’s maximum health.
Tocotrienols are 50-60 X more powerful Antioxidants than the synthetic “dl”-Tocopherols found in all common vitamin E pills.
Life’s “Gatekeepers” are the Membranes of our cells controlling all substances going into and out of every cell and tissue in our body.
Delta- and Gamma- Tocotrienols are the ultimate Bodyguards of our GateKeepers protecting them from destructive “Free Radicals”.
In 2009, a World Patent (WO2009126866 A2.) was granted for “Delta-Tocotrienol As A Radioprotective Countermeasure Agent” that significantly protects the subject from “Ionizing Radiation”, which includes alpha- radiation, beta- radiation, gamma- radiation, X-rays, Ultra-Violet radiation and Neutrons. (see below)
In 2014, a U.S. Patent (US 8,846,653 B2) was issued: “Delta-Tocotrienol Treatment and Prevention of Pancreatic Cancer”. (see below).
Tocotrienols inhibit the Oxidation of LDL (bad) cholesterol, inhibit the “Velcro” effect of Monocytes on the Endothelium, Lower Triglycerides, while Promoting our Cardiovascular health.
GG Promotes our body’s energy via CoQ10 Synthesis and Prevents Statin drug side effects and Protects Osteocytes in our Bones.
Tocotrienols and GG essentially benefit all of our cells, tissues, organs.
Taking Tocotrienols with GG together provides Two of the Best Natural Nutrients for Protection and Maintenance for our entire Long Life.
An additional health benefit: Human Skin Loves Tocotrienols.
Tocotrienols
Some Benefits of Tocotrienols are:
Powerful Antioxidant: Delta tocotrienols exhibit strong antioxidant properties, helping to neutralize harmful free radicals in the body.
Heart Health: They may support cardiovascular health by reducing cholesterol levels, improving blood vessel function, and reducing the risk of plaque buildup in arteries.
Potential Cancer Prevention: Some studies suggest that delta tocotrienols may have anti-cancer properties, potentially inhibiting the growth of cancer cells.
Brain Health: Delta tocotrienols may support cognitive function and protect brain cells from oxidative damage, potentially reducing the risk of neurodegenerative diseases.
Radiation Protection: Studies suggest that tocotrienols may offer protective effects against radiation exposure, helping to mitigate damage to cells.
Geranylgeraniol
Some Benefits of Geranylgeraniol are:
Coenzyme Q10 (CoQ10) Production: Geranylgeraniol is a precursor molecule that supports the body's natural production of Coenzyme Q10, which is essential for cellular energy production.
Essential for Energy Production: GG is vital for synthesizing CoQ10, which our mitochondria use to generate ATP, the body’s primary energy source.
Heart Health: CoQ10 produced from Geranylgeraniol may help improve cardiovascular health by supporting proper heart function and blood vessel health.
Antioxidant Support: Geranylgeraniol may help protect cells from oxidative damage by promoting the production of antioxidant enzymes.
Potential Cancer Prevention: There is ongoing research into Geranylgeraniol's potential role in inhibiting the growth of cancer cells, especially in certain cancer types.
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Tocotrienols Provide Radioprotection to Multiple Organ Systems (2023)
Tocotrienols have powerful radioprotective properties in multiple organ systems and are promising candidates for development as clinically effective radiation countermeasures. To facilitate their development as clinical radiation countermeasures, it is crucial to understand the mechanisms behind their powerful multi-organ radioprotective properties. In this context, their antioxidant effects are recognized for directly preventing oxidative damage to cellular biomolecules from ionizing radiation.
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U.S. Patent: Delta Tocotrienol As A Radioprotective Countermeasure Agent (2009)
A method for treating the effects of radiation in a subject, comprising administering to the subject a composition comprising a radioprotective amount of delta-tocotrienol or a derivative thereof. Wherein ionizing radiation is alpha radiation, beta radiation, gamma radiation, X-radiation, ultra-violet radiation, and neutrons.
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U.S. Patent: Delta-Tocotrienol Treatment and Prevention of Pancreatic Cancer (2012)
Tocotrienols, the chemical form of vitamin E with an unsaturated isoprenoid side chain, are receiving attention as promising dietary supplements for cancer prevention and treatment.
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Tocotrienols as an Anti-Breast Cancer Agent (2021)
One group of natural compounds in particular, tocotrienols, has demonstrated significant potential as an anti-breast cancer agent . Known for their potent antioxidant activity, the innate anticancer properties of these unsaturated isoforms of vitamin E are often overlooked. This review will summarize current evidence and the potential of tocotrienols as an anticancer agent
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Neuroprotective and Anti-Obesity Effects of Tocotrienols (2019)
Vitamin E is a natural lipophilic vitamin, and the most famous function of vitamin E is an antioxidant activity. Because we have α-tocopherol transfer protein, many vitamin E-related reports are about α-tocopherol. Recently, other vitamin E isoforms, tocotrienols are focusing. Because tocotrienols have unique biological functions such as induction of apoptosis, neuroprotective and anti-obesity effects.
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Anti-Aging Potentials of Tocotrienol (2021)
The tocotrienols have been identified as an anti-aging agent and thus implicated in improving overall quality of life by reducing the incidences of these deleterious diseases and disorders. They also protect and prevent against ultraviolet (UV)-induced skin damage and aging.