Radiation Protection
The U.S. Armed Forces Radiobiology Research Institute (AFRRI) in Bethesda, Maryland, has extensively researched radiation protection. Among natural agents, Vitamin E Tocotrienols, especially Delta- and Gamma-Tocotrienols, proved highly effective. They act as potent antioxidants and stimulate bone marrow's hematopoietic tissues, aiding in the restoration of a damaged blood supply caused by radiation. In animal studies, Tocotrienols nearly normalized White Blood Cells, Neutrophils, and Platelets following Ionizing Radiation, with Delta-Tocotrienol notably regenerating lymphocytes. Prophylactic Delta-Tocotrienol treatment, administered 24 hours before radiation exposure, showed better results than post-radiation treatment. This suggests potential use as a preoperative radioprotector for radiation workers in various industries, hospitals, astronauts, pilots, crew members, and cancer therapy patients. Tocotrienols safeguard sensitive cells from Ionizing Radiation, including Alpha, Beta, Gamma, X-ray, Ultraviolet, and Neutrons, which produce harmful Free Radicals, inflammation, and cellular damage. AFRRI has published numerous studies confirming Tocotrienols' protective effects. Considering Tocotrienol supplementation before potential radiation exposure is advisable during air travel, medical imaging, high-altitude activities, or work near radiation-producing equipment.
References
Radiation Research (2024) - Modulation of Hematopoietic Injury by a Promising Radioprotector, Gamma-Tocotrienol, in Rhesus Macaques Exposed to Partial-Body Radiation
Antioxidants (2023) - Tocotrienols Provide Radioprotection to Multiple Organ Systems through Complementary Mechanisms of Antioxidant and Signaling Effects
Scientific Reports (2022) - Gamma-tocotrienol, a radiation countermeasure, reverses proteomic changes in serum following total-body gamma irradiation in mice
Journal of Radiation & Cancer Research (2020) - Novel approach to mitigate radiation overexposure, α-, δ-Tocotrienol as radiation mitigator: A case report
International Journal of Molecular Science (2016) - γ-Tocotrienol as a Promising Countermeasure for Acute Radiation Syndrome: Current Status
Radiation Research (2015) - A Tocotrienol-Enriched Formulation Protects against Radiation-Induced Changes in Cardiac Mitochondria without Modifying Late Cardiac Function or Structure
PLOS ONE (2015) - Delta-Tocotrienol Suppresses Radiation-Induced MicroRNA-30 and Protects Mice and Human CD34+ Cells from Radiation Injury
Life Sciences (2014) - Radioprotective efficacy of delta-tocotrienol, a vitamin E isoform, is mediated through granulocyte colony-stimulating factor
Journal of Radiation Research (2013) - Vitamin E: tocopherols and tocotrienols as potential radiation countermeasures
Tocotrienol Patent (2013) - Agent with tocotrienol for burns from the sun, radioactive rays or heat