Tocotrienols & Bone Research

Explore published studies examining tocotrienols in relation to bone metabolism and osteoporosis. Visit each source for its methods, findings, and limitations.

References

Updates in the Skeletal and Joint Protective Effects of Tocotrienol: a Mini Review (2024) https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2024.1417191/full?utm_source=chatgpt.com

Tocotrienol as a Protecting Agent against Glucocorticoid-Induced Osteoporosis: A Mini Review of Potential Mechanisms (2022)

https://www.mdpi.com/1420-3049/27/18/562?utm_source=chatgpt.com

Tocotrienol Supplementation Led to Higher Serum Levels of Lysophospholipids but Lower Acylcarnitines in Postmenopausal Women: A Randomized Double-Blinded Placebo-Controlled Clinical Trial (2021) https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2021.766711/full?utm_source=chatgpt.com

Therapeutic potential of Annatto Tocotrienol with self-emulsifying drug delivery system in a rat model of postmenopausal bone loss (2021)

https://www.sciencedirect.com/science/article/pii/S0753332221001530?utm_source=chatgpt.com

Osteoprotective Effects in Postmenopausal Osteoporosis Rat Model: Oral Tocotrienol vs. Intraosseous Injection of Tocotrienol-Poly Lactic-Co-Glycolic Acid Combination (2021)

https://pmc.ncbi.nlm.nih.gov/articles/PMC8637158/?utm_source=chatgpt.com

Tocotrienol supplementation suppressed Bone Resorption and Oxidative Stress in Postmenopausal Osteopenic Women: a 12-week randomized double-blinded placebo-controlled trial (2018)  

https://pubmed.ncbi.nlm.nih.gov/29330573/

The biological effects of tocotrienol on bone: a review on evidence from rodent models (2015) https://pmc.ncbi.nlm.nih.gov/articles/PMC4396581/?utm_source=chatgpt.com
γ-Tocotrienol protects against ovariectomy-induced bone loss via mevalonate pathway as HMG-CoA reductase inhibitor (2014)

https://pubmed.ncbi.nlm.nih.gov/25019595/

Effects of Low-Dose versus High-Dose γ-Tocotrienol on the Bone Cells Exposed to the Hydrogen Peroxide-Induced Oxidative Stress and Apoptosis (2012) 

https://pmc.ncbi.nlm.nih.gov/articles/PMC3432387/?utm_source=chatgpt.com

α-Tocotrienol inhibits osteoclastic bone resorption by suppressing RANKL expression and signaling and bone resorbing activity (2011).

https://www.sciencedirect.com/science/article/abs/pii/S0006291X11002907?utm_source=chatgpt.com